- 5 mg per vial
Free & Fast
Free & Fast
|Heavy Atom Count||64|
|Hydrogen Bond Donor Count||11|
|Hydrogen Bond Acceptor Count||9|
|Rotatable Bond Count||23|
|Physical Appearance||Fine White Lyophilized Powder|
|Stability||Lyophilized protein is to be stored at -20°C. It is recommended to aliquot the reconstituted (dissolved) protein into several discrete vials in order to avoid repeated freezing and thawing. Reconstituted protein can be stored at 4°C|
|PubChem LCSS||GHRP-6 Laboratory Chemical Safety Summary|
|InChI||InChI=1S/C46H56N12O6/c1-27(54-44(62)39(20-29-23-51-35-15-7-5-13-32(29)35)57-43(61)34(48)22-31-25-50-26-53-31)42(60)56-40(21-30-24-52-36-16-8-6-14-33(30)36)46(64)58-38(19-28-11-3-2-4-12-28)45(63)55-37(41(49)59)17-9-10-18-47/h2-8, 11-16, 23-27, 34, 37-40, 51-52H, 9-10, 17-22, 47-48H2, 1H3, (H2, 49, 59)(H, 50, 53)(H, 54, 62)(H, 55, 63)(H, 56, 60)(H, 57, 61)(H, 58, 64)/t27-, 34-, 37-, 38+, 39+, 40-/m0/s1|
Generated by Extreme Peptide with Open Babel, version 2.3.1, http://openbabel.org (accessed June 28, 2022)
Growth Hormone Releasing Peptide 6 (GHRP-6) is a synthetic, 6-amino acid sequence, which is analogous to the naturally occurring protein met-enkephalin1. GHRP-6 is a member of a classification of agents called growth hormone (GH) secretagogues that were collectively developed in an effort to artificially stimulate the release of GH2. GHRP-6 is known to bind with the GH secretagogue receptor (ghrelin receptor) directly3, stimulating potent GH secretion and appetite in animal test subjects2.
The promotion of improved strength, increased muscle mass to body fat ratio, and the encouragement of good joint and connective tissue health has been observed in animal trials4.
Similar to other agents of GH release, GHRP-6 acts on the anterior pituitary gland5. In spite of having a similar site of action, GHRP-6 does not stimulate GH production using the same biochemical pathway as the popular GH secretagogue ‘sermorelin’ its analogues, like CJC-12956. In light of this observation, it has been possible for researchers to administrate CJC-1295 and GHRP-6 concurrently in order to achieve an additive positive effect on GH release. A similar synergistic relationship has been documented with insulin, where much improved GH release was observed in animal trials following a concurrent dosing scheme7.
The GHRP family of proteins is distinct from growth hormone releasing hormones (GHRH or GHRF) in that they share no sequence relation and derive their function through action at a completely different receptor, the ghrelin receptor8. The GHRP family is unique in that they lack opiate activity, though they are analogues of species that bear this quality9.
Growth Hormone Releasing Peptide-6; Growth hormone releasing hexapeptide; Somacrin; Somatocrinin-6; RP6;
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